"The
Report Ovarian Cancer Therapeutics in Asia-Pacific Markets to 2020 -
Off-patent Chemo-regimens to Retain Dominance Despite New Launches
provides information on pricing, market analysis, shares, forecast,
and company profiles for key industry participants. -
MarketResearchReports.biz"
GBI
Research, a leading business intelligence provider, has released its
latest research report: “Ovarian Cancer Therapeutics in
Asia-Pacific Markets to 2020 - Off-patent Chemo-regimens to Retain
Dominance Despite New Launches”. The report provides estimates of
the market size for 2013, along with forecasts until 2020 for the
Asia-Pacific markets of India, China, Australia and Japan. It also
covers disease epidemiology, treatment algorithms, treatment
patterns, in-depth analysis of clinical trials including failure
rates and pipeline analysis, and analysis of deals relevant to
Ovarian Cancer (OC).
Platinum-based
chemotherapy, predominantly the chemotherapy regimen paclitaxel and
carboplatin, is the standard of care for the treatment of
platinum-sensitive OC (both first-line and recurrent). The initial
treatment is quite effective, with the majority of patients entering
remission. However, almost all relapse, and after successive periods
of remission and relapse either die or progress to platinum-resistant
disease, for which the prognosis is poor. There is a clear gap in the
market for maintenance therapies, as well as for more effective
treatment options in platinum-resistant or refractory patients.
Although
the current developmental pipeline is quite crowded, efficacy with
these late-stage drugs has been poor, at best demonstrating minimal
improvements in progression-free survival, but not overall survival.
The promising investigational drug candidates olaparib and trebananib
are expected to gain approval during the forecast period. However,
even on approval they are not expected to have a high market
penetration, owing to their minimal therapeutic efficacy and
anticipated premium prices. As a result, the OC market in APAC is
expected not be driven by new drug approvals, but primarily by
inflation, and the increase in the prevalence of OC. Market revenue
is forecast to rise at a limited CAGR of 5.1% to $417.6m in 2020.
Despite
the poor clinical performance of current late-stage pipeline drugs,
there is evidence of continued interest in the OC market, with a high
number of drug candidates in the initial developmental pipeline,
particularly at the Preclinical phase. There is a wide range of novel
molecular targets distributed among these drug candidates, including
growth factors, serine/threonine protein kinases and tumor associated
antigens. This suggests a continued interest in introducing more
targeted therapies into the treatment of OC, the use of which in this
indication lags significantly behind that in others in oncology.
View Report At
http://www.marketresearchreports.biz/analysis/242400
Scope
The report analyzes treatment
usage patterns, drug types available and pipeline and market
forecasts for OC. It covers and includes:
- A brief introduction to OC, including the disease’s pathogenesis, risk factors and diagnosis
- In-depth analysis of the drug combinations used in the treatment of OC, including analyses of their safety, efficacy, and place in the disease treatment algorithm, as well as a heat map comparing the drug combinations in terms of safety and efficacy
- A comprehensive review of the pipeline for OC therapies, including individual analysis of a number of late-stage pipeline drugs that have the potential to enter the market in the forecast period; the pipeline is analyzed on the basis of phase distribution, molecule type and molecular target, and route of administration
- Additional in-depth analysis of pipeline drug clinical trials by phase, molecule type, trial size, and trial duration, and program failure rate analyses for each molecule type and mechanism of action
- Multi-scenario forecast market data to 2020, taking into account how it will be affected by the introduction of new drugs, the expiry of key patents on current drugs, and the changes in disease epidemiology across the APAC markets
- Discussion of the drivers and barriers for market growth
- In-depth analysis of licensing and co-development deals involving drugs indicated in OC, including an outline of the key deals
Reasons To Buy
The report will assist business
development and enable marketing executives to strategize their
product launches, by allowing them to:
- Understand the efficacy and safety of the current monotherapies and drug combinations used in the treatment of OC, with in-depth analysis of the disease treatment algorithm
- Understand the key signaling pathways and molecular targets currently under investigation in OC drug development
- Understand the vast scope of the pipeline, including which molecule types and mechanisms of action are prominent
- Observe the trends in clinical trial duration and size among clinical phases and molecule types, and use the clinical trial failure rate analysis to assess the risk profiles of current and/or future developmental programs for OC therapeutics
- Assess the potential clinical and commercial impact of current late-stage pipeline molecules in the OC therapeutics market
Download
Sample copy of this Report at :
Table
of Contents
1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Introduction
2.1 Disease Pathophysiology
2.1.1 Ovarian Cancer – A Group
of Distinct Diseases
2.1.2 Ovarian Cancer is Highly
Heterogenic with Multiple Mutations and Affected Signaling Pathways
2.2 Symptoms and Diagnosis
2.3 Risk Factors
2.3.1 Age
2.3.2 Inherited Genetic Mutations
2.3.3 Greater Number of Lifetime
Ovulations
2.3.4 Weight
2.3.5 Previous Medical Conditions
2.4 Treatment Algorithm
2.4.1 Surgery
2.4.2 First-Line Chemotherapy
2.4.3 Maintenance Therapy
2.5 Recurrent Disease
3 Marketed Products
3.1 Carboplatin
3.2 Paclitaxel
3.3 Gemcitabine
3.4 Topotecan
3.5 Pegylated Liposomal
Doxorubicin
3.6 Yondelis
3.7 Avastin
4 Product Pipeline
4.1 Overview of Pipeline by Phase
and Route of Administration
4.2 Overview of Pipeline by
Molecule Type, Mechanism of Action and Molecular Target
4.2.1 Molecular Targets in the
Developmental Pipeline
4.3 Clinical Trials
4.3.1 Clinical Trial Duration
4.3.2 Clinical Trial Size
4.3.3 Failure Rate
4.3.4 Discussion
4.4 Late-Stage Drugs in
Developmental Pipeline
4.4.1 Niraparib
4.4.2 Olaparib
4.4.3 Vargatef
4.4.4 Trebananib
4.4.5 Farletuzumab
4.4.6 Karenitecin
4.5 Discussion
5 Market Forecasts
5.1 Asia-Pacific
5.1.1 Overview
5.1.2 Treatment Use Patterns and
Revenues in Asia-Pacific Markets
5.2 India
5.2.1 Treatment Use Patterns
5.2.2 Annual Cost of Therapy
5.2.3 Market Forecast
5.3 China
5.3.1 Treatment Use Patterns
5.3.2 Annual Cost of Therapy
5.3.3 Market Forecast
5.4 Japan
5.4.1 Treatment Use Patterns
Read our latest Press Release
at http://www.marketresearchreports.biz/pressreleases
About
us
MarketResearchReports.biz
is the most comprehensive collection of market research reports.
MarketResearchReports.Biz services are specially designed to save
time and money for our clients. We are a one stop solution for all
your research needs, our main offerings are syndicated research
reports, custom research, subscription access and consulting
services. We serve all sizes and types of companies spanning across
various industries.
Contact
State
Tower
90
Sate Street, Suite 700
Albany,
NY 12207
Tel:
+1-518-621-2074
No comments:
Post a Comment